Malignant Mesothelioma Market Size 2025-2035, Epidemiology, Drugs Treatment & Companies

 The malignant mesothelioma market size reached a value of USD 6.5 Billion across the top 7 markets (US, EU4, UK, and Japan) in 2024. Looking forward, IMARC Group expects the top 7 major markets to reach USD 12.8 Billion by 2035, exhibiting a growth rate (CAGR) of 6.3% during 2025-2035.

As diagnosed cases increase, with more effective treatments being developed and diagnostic capabilities improving, the malignant mesothelioma market is set to receive greater focus in 2025. It is a rare form of cancer with a very aggressive pathology, often caused by asbestos exposure, and affects the lung lining, abdomen, and heart. The low incidence rate due to lack of awareness has started changing, which in turn is leading to increased investment in care solutions globally.

Shrinking Lag Time & Increasing Awareness

While the malignant mesothelioma is still on the rise, there is hope in the form of a pending public health initiative. In countries where asbestos is banned, the malignant mesothelioma growth rate is positively affected due to lack of exposure, as one key element of the silence is removed. Finally, increased knowledge and awareness among the professional health community is helping in the early detection, which is vital to bolster market demand.

Increased investment and awareness at the political level is further driving the growth of the market. Comprehensive screening targeting groups such as previous shipyard workers, construction workers and people from regions with high rates of asbestos use are aiding in the identification of malignant mesothelioma cases. Although a definitive cure may still be focused on, early on in the treatment process malignancies can be managed to improve the quality of life for patients.

New Methods of Treatment  

For a long time, mesothelioma care has relied on platinum-based chemotherapy. However, the emergence of immunotherapy is changing the paradigm. By 2025, its preferred use in newly diagnosed patients will be in combination with immune checkpoint inhibitors PD-1 and CTLA-4, demonstrating improved survival rates and tolerable side effects in comparison to chemotherapy alone. Progress is also being made in targeted therapies. Work persists on specific tumor markers and genetic profiles associated with mesothelioma, such as BAP1 mutations, mesothelin, and angiogenesis pathways. The late-stage trials of drugs targeting these markers, with or without chemotherapy, offer hope for more tailored treatment regimens.  

Technological Innovations in Diagnostics   

Timely and accurate diagnosis is critical in mesothelioma management, and new technologies are improving accuracy. Advanced imaging, such as PET-CT and high-resolution MRI with diffusion-weighted imaging, is enhancing disease-staging accuracy, therefore, improving treatment planning. Furthermore, the liquids biopsies measuring circulating tumor DNA are emerging as non-invasive methods to track disease progression and assess response to treatment. The fields of digital histopathology and artificial intelligence are revolutionizing pathology. These technologies assist pathologists in differentiating mesothelioma from other cancers using tissue samples with more precision. AI-boosted diagnostics provide greater accuracy in cancer diagnosis and biopsy to treatment timelines.  

Market Outlook and Future Directions  

An increase in the malignant mesothelioma market's growth rate is anticipated within the next few years. There is growing interest in innovative methods for early diagnosis, advanced immunotherapy and targeted therapy, as well as integrated multi-disciplinary treatment approaches. There is an emerging trend of collaboration between oncologists, pulmonologists, radiologists, and pathologists which is leading to the establishment of multidisciplinary centers of excellence that offer holistic patient care.  

These platforms are not only offering remote second opinion consultations but are also helping patients get connected with clinical trials all over the world which allows them to participate regardless of where they live. Long-term outcome registries are being set up to capture and track treatment data over extended periods, thus enhancing real-world evidence research that informs future strategy on development for treatments and methods of reimbursement.

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Countries Covered:

• United States
• Germany
• France
• United Kingdom
• Italy
• Spain
• Japan

Analysis Covered Across Each Country:

• Historical, current, and future epidemiology scenario
• Historical, current, and future performance of the malignant mesothelioma market
• Historical, current, and future performance of various therapeutic categories in the market
• Sales of various drugs across the malignant mesothelioma market
• Reimbursement scenario in the market
• In-market and pipeline drugs

This report also provides a detailed analysis of the current malignant mesothelioma marketed drugs and late-stage pipeline drugs.

In-Market Drugs:

• Drug Overview
• Mechanism of Action
• Regulatory Status
• Clinical Trial Results
• Drug Uptake and Market Performance

Late-Stage Pipeline Drugs:

• Drug overview
• Mechanism of action
• Regulatory status
• Clinical trial results
• Drug uptake and market performance

Competitive Landscape with key players:

The competitive landscape of the malignant mesothelioma market has been studied in the report with the detailed profiles of the key players operating in the market.

1. Bristol Myers Squibb

2. Bristol-Myers Squibb/Ono Pharmaceuticals

3. Momotaro-Gene

4. RS Oncology

5. AstraZeneca

6. Merck & Co

7. Bristol-Myers Squibb

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IMARC Group is a global management consulting firm that helps the world’s most ambitious changemakers to create a lasting impact. The company provide a comprehensive suite of market entry and expansion services. IMARC offerings include thorough market assessment, feasibility studies, company incorporation assistance, factory setup support, regulatory approvals and licensing navigation, branding, marketing and sales strategies, competitive landscape and benchmarking analyses, pricing and cost research, and procurement research.

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