Non-Cystic Fibrosis Bronchiectasis (NCFB) Market Size, Epidemiology, Trends, and Forecast 2025-2035
The 7 major non-cystic fibrosis bronchiectasis (NCFB) markets reached a value of USD 1,661.7 Million in 2024. Looking forward, IMARC Group expects the 7MM to reach USD 6,901.9 Million by 2035, exhibiting a growth rate (CAGR) of 13.78% during 2025-2035.
NCFB is a progressive lung disease where there is persistent airway dilatation that leads to mucus plugging, repeated infection, and inflammation. This would mean that unlike cystic fibrosis-associated bronchiectasis, none of the treatments available is approved explicitly for NCFB, giving rise to an appreciable unmet medical need. Significant progress was mapped out in 2024 when Insmed's brensocatib was shown effective in a Phase 3 trial. As a first-in-class dipeptidyl peptidase 1 (DPP1) inhibitor, it drastically reduced the number of pulmonary exacerbations in patients with NCFB. In light of the successful outcomes, Insmed had submitted a New Drug Application to the FDA, with a likely U.S. launch by mid-2025
Advances in diagnostic technologies are also redefining management of NCFB. High-resolution computed tomography (HRCT) enables visualization of subtle bronchial abnormalities, making earlier and more precise diagnoses possible. Molecular diagnostics such as polymerase chain reaction (PCR) and next-generation sequencing (NGS) permit identification of pathogens and antibiotic resistance patterns with accuracy. Artificial intelligence (AI) is also being used to improve imaging analysis, ensuring consistency and assisting with treatment planning. The current treatment approaches are symptom-oriented, targeting inhaled antibiotics, airway clearance therapy, and anti-inflammatory drugs. Smart inhalers and remote monitoring devices are on the horizon, enabling real-time analysis of respiratory metrics and tailored adjustments to therapy. Telemedicine platforms are also broadening access to specialized care, especially in remote areas.
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Countries Covered
- United States
- Germany
- France
- United Kingdom
- Italy
- Spain
- Japan
Analysis Covered Across Each Country
- Historical, current, and future epidemiology scenario
- Historical, current, and future performance of the non-cystic fibrosis bronchiectasis (NCFB) market
- Historical, current, and future performance of various therapeutic categories in the market
- Sales of various drugs across the non-cystic fibrosis bronchiectasis (NCFB) market
- Reimbursement scenario in the market
- In-market and pipeline drugs
Competitive Landscape
This report also provides a detailed analysis of the current non-cystic fibrosis bronchiectasis (NCFB) marketed drugs and late-stage pipeline drugs.
In-Market Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
Late-Stage Pipeline Drugs
- Drug Overview
- Mechanism of Action
- Regulatory Status
- Clinical Trial Results
- Drug Uptake and Market Performance
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